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相关概念视频

Inheritance01:25

Inheritance

379
Gregor Mendel's pioneering work on the principles of inheritance fundamentally transformed our understanding of how traits are transmitted from generation to generation. His experiments with pea plants laid the groundwork for the discovery of genes, discrete units within organisms that control heredity.
Each gene exists in pairs, and the combination of these genes from both parents forms an individual's genotype. This genotype is a blueprint of potential traits. Examples of genotype...
379
Pedigree Analysis01:35

Pedigree Analysis

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Overview
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Law of Segregation01:49

Law of Segregation

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When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.
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Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

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Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
34.3K
Chromosomal Theory of Inheritance01:39

Chromosomal Theory of Inheritance

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In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”
55.3K
Probability Laws01:49

Probability Laws

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相关实验视频

Updated: Jun 24, 2025

High-throughput Screening for Protein-based Inheritance in S. cerevisiae
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从父母到后代,从父母到后代.

Sara Shama1, Michelle R Asbury2, Deborah L O'Connor3

  • 1Department of Nutritional Sciences, University of Toronto, Toronto, Canada; Translational Medicine Program, SickKids Research Institute, The Hospital for Sick Children, Toronto, Canada.

Cell host & microbe
|June 13, 2024
PubMed
概括

婴儿的肠道微生物组是由父母的微生物塑造的. 了解这种传播是婴儿健康和发育的关键.

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科学领域:

  • 微生物学 微生物学
  • 人类微生物组 人类微生物组
  • 儿科 儿科 儿科

背景情况:

  • 建立婴儿肠道微生物社区对于免疫系统发育和整体健康至关重要.
  • 影响微生物从父母传播给婴儿的因素尚未完全理解.

研究的目的:

  • 研究微生物群落从父母传给婴儿的传播动态.
  • 确定改变婴儿在生命早期肠道微生物组合的关键因素.

主要方法:

  • 利用猎枪元基因组测序来分析来自父母和婴儿样本的微生物DNA.
  • 采用先进的生物信息学来评估微生物社区结构并确定传播来源.

主要成果:

  • 从母亲和父亲向婴儿直接传播特定的微生物物种.
  • 确定了分娩方式和早期暴露作为婴儿肠道微生物殖民的显著调节者.

结论:

  • 父母的微生物播种在塑造婴儿肠道微生物群中发挥着至关重要的作用.
  • 环境和生活方式因素与遗传倾向相互作用,影响婴儿微生物社区的发展.