在增量循环人体体测量过程中,动态启发性约束的性别和年龄调整的参考值
Abed A Hijleh1, Danilo C Berton2, Igor Neder-Serafini1
1Respiratory Investigation Unit, Division of Respirology, Department of Medicine, Queen's University, Kingston General Hospital, Connell 2-200. 102 Stuart St., Kingston, ON K7L 2V7, Canada.
Respiratory physiology & neurobiology
|June 13, 2024
概括
对于炼呼吸储备 (IR) 的新参考值有助于评估肺部疾病中的呼吸困难. 这些动态IR指标,IRdyn1和IRdyn2,在女性和老年人中较低,并预测呼吸障碍的严重程度.
科学领域:
- 肺部生理学 肺部生理学
- 运动医学 运动医学
背景情况:
- 在慢性肺病中,与活动相关的呼吸障碍与动态吸气约束有关.
- 炼启发性储备 (IR) 的有限参考值阻碍了心肺运动测试 (CPET) 来评估呼吸障碍.
研究的目的:
- 在运行期间为动态启发性储备 (IRdyn) 建立基于百分点的参考值.
- 评估IRdyn指标和运动性呼吸障碍之间的关系.
主要方法:
- 150名健康的成年人 (40-85岁) 进行了增量周期人体体力学.
- 动态启发性储备指标 (IRdyn1,IRdyn2) 根据行使启发性能力 (ICdyn) 计算.
- 性别和年龄特定的参考值是作为通风的函数生成的.
主要成果:
- 在女性和老年人中,IRdyn1和IRdyn2的参考值较低.
- 较低的IRdyn1和IRdyn2显著预测了两种性别的运动性呼吸障碍的严重程度.
- 建立了根据性别和年龄调整的参考界限.
结论:
- 动态启发性储备的新性别和年龄调整的参考值改善了CPET的解释.
- 这些指标有助于临床医生识别和量化呼吸障碍患者异常低的呼吸储量.
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