2013年至2018年期间,欧洲异形性肺纤维化病的死亡率趋势
Francesca Gonnelli1,2, Martina Bonifazi2,3, Richard Hubbard4
1Lifespan and Population Health, University of Nottingham, Nottingham, UK Francesca.Gonnelli@nottingham.ac.uk.
The European respiratory journal
|June 13, 2024
概括
异形性肺纤维化 (IPF) 的死亡率正在欧洲各地上升,每年有超过17000人死亡. 存在显著的地理差异,这表明当前的数据可能低估了这种进展性肺部疾病的真正负担.
科学领域:
- 肺部病理学 肺部病理学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 据报道,在全球范围内,异形性肺纤维化 (IPF) 的发病率正在增加.
- 了解目前的IPF死亡率趋势对于公共卫生规划至关重要.
研究的目的:
- 为了估计24个欧盟国家的当代IPF死亡率.
- 分析IPF死亡率在2013年至2018年的趋势和地理变化.
主要方法:
- 使用了欧洲统计机构 (EUROSTAT) 的死亡证明数据 (ICD-10:J84.1).
- 计算国家,年龄和性别特定的死亡率.
- 使用直接标准化和细分回归来分析趋势.
主要成果:
- 总体标准化死亡率为每10万人年3.90 (2013-2018).
- 死亡率从2013年的3.70增加到2018年的4.00 (年变化为1.74%).
- 爱尔兰,英国和芬兰的比率最高,保加利亚的比率最低. 观察到显著的地理差异.
结论:
- 在整个欧洲,IPF的死亡率正在增加.
- 每年记录的死亡人数超过17000人,但地理位置的差异表明这一数字被低估了.
- 进一步研究区域差异和报告不足是有必要的.
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