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十几岁的青少年发生自发双边松状结质血栓形成
Esther Ern Hwei Chan1, Fay Xiangzhen Li2, Matthew Chien Ern Goh3
1Department of Paediatric Surgery, KK Women's and Children's Hospital, Singapore esther.chan.e.h@kkh.com.sg.
BMJ case reports
|June 13, 2024
概括
一个罕见的疾病,即自发的松状结质血栓症,在一个青少年身上通过阴囊超声波诊断出来. 保守的管理导致了完全的分辨率,突出了超声波.
科学领域:
- 血管外科 血管外科
- 儿科泌尿外科 儿科泌尿外科
- 放射学 放射学是一门学科.
背景情况:
- 自发松状结质血栓症 (SPPT) 是一种非常罕见的疾病,其病因和病理生理不明.
- 诊断SPPT往往是具有挑战性的,有助于有限的理解和治疗指南.
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Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
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The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
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