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Updated: Jun 24, 2025

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
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在血液和胰腺的自反应性T细胞之间共享的生殖线样TCR-α链

Peter S Linsley1, Maki Nakayama2, Elisa Balmas3

  • 1Benaroya Research Institute at Virginia Mason, Seattle, WA, USA. plinsley@benaroyaresearch.org.

Nature communications
|June 13, 2024
PubMed
概括

研究人员发现,1型糖尿病 (T1D) 患者血液中的T细胞与胰腺中发现的T细胞共享独特的T细胞受体 (TCR) 序列. 这一发现将外围T细胞与T1D中的胰腺T细胞联系起来.

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