早期的血管衰老由脚脉冲波速和其对缺血性中风结果的影响决定:一项回顾性观察性研究
Minho Han1,2, Jaeseob Yun1, Kwang Hyun Kim1
1Department of Neurology, Yonsei University College of Medicine, 50-1 Yonsei-Ro, Seodaemoon-Gu, Seoul, 03722, South Korea.
Scientific reports
|June 13, 2024
概括
早期血管衰老 (EVA),由脚脉冲波速度确定,预测急性缺血性中风患者的不良结果和死亡率. 这种血管衰老表型有助于识别患中风并发症风险较高的个体.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 老年学是一门学科.
背景情况:
- 血管衰老是心血管健康的一个重要因素.
- 预测中风预后对于患者管理至关重要.
- 腕脉冲波速度 (baPWV) 是血管衰老的标志物.
研究的目的:
- 研究血管衰老表型与急性缺血性中风患者的结果之间的关系.
- 为了确定早期血管衰老 (EVA) 是否与功能不良的结果和死亡率有关.
- 评估血管衰老表型在识别高风险中风患者中的有用性.
主要方法:
- 分析了2738名急性缺血性中风患者的队列.
- 血管衰老的表型被评估使用腕脉冲波速度 (baPWV).
- 根据特定年龄的baPWVs,患者被分为超正常 (SUPERNOVA),正常 (NVA) 和早期血管衰老 (EVA) 组.
主要成果:
- 早期血管衰老 (EVA) 与3个月后功能表现不佳有关 (OR 2.083).
- EVA与所有原因死亡率 (HR 2.320) 有显著的联系.
- 在患有同时存在糖尿病或心房的患者中,EVA与不良结局的关联更加明显.
结论:
- 血管衰老表型,特别是EVA,是急性缺血性中风后不良结果和死亡率的有价值预测因素.
- EVA可以帮助临床医生识别高风险中风患者.
- 对管理EVA的进一步研究可能会改善中风预后.
相关概念视频
01:23Assessment of blood pressure in brachial artery(two-step method)
689
Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
689
01:15Assessment of blood pressure in brachial artery(one-step method)
580
This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
Prepare for the Procedure:
580
01:21Sites for measruring blood pressure
1.6K
Blood pressure measurement is a fundamental clinical procedure, providing crucial data for assessing cardiovascular health. Among the various sites for this measurement, the brachial and popliteal arteries are predominantly utilized due to their accessibility and the reliability of their readings. This lesson delves into the anatomical significance, methodology, and considerations of measuring blood pressure at these locations.
The Brachial Artery: Primary Site for Blood Pressure Measurement
The Brachial Artery: Primary Site for Blood Pressure Measurement
1.6K
01:16Pulse
498
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...
The pulse serves as a clinical...
498
01:27Regulation of Stroke Volume
3.2K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
3.2K