影响美国人口中抑郁症状和心血管疾病之间的关联的因素
Keming Ren1, Yan Ma2,3, Shuaijie Chen4
1Department of Psychiatry, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, 310000, Zhejiang, China.
Scientific reports
|June 13, 2024
概括
更严重的抑郁症状增加了心血管疾病 (CVD) 的风险. 这种关联取决于剂量,并受到性别,糖尿病,收入和饮食等因素的影响.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 心脏病学 心脏病学
背景情况:
- 心血管疾病 (CVD) 和抑郁症是具有重大健康影响的普遍疾病.
- 虽然抑郁症和心血管疾病之间存在联系,但社会经济因素,病史和饮食的影响需要进一步调查.
研究的目的:
- 分析美国成年人抑郁症状与心血管疾病风险之间的关联.
- 探索社会经济地位,病史和饮食摄入量对这种关联的影响.
主要方法:
- 利用了2007-2016年国家健康和营养检查调查 (NHANES) 的数据.
- 在11516名40岁及以上的参与者中使用复杂的抽样加权后勤回归模型.
- 在不同程度的抑郁症状中评估心血管疾病的几率比率 (ORs).
主要成果:
- 在抑郁症状和心血管疾病风险之间观察到剂量依赖的关系.
- 与轻度,中度和重度抑郁症的参与者相比,轻度,中度和重度抑郁症的参与者分别增加了1.25,1.98和2.41的OR,与抑郁症最小的参与者相比.
- 在抑郁症状与性别,糖尿病,家庭收入和饮食中的胆固醇摄入量之间发现了与心血管疾病风险有关的显著相互作用.
结论:
- 抑郁症状的严重程度增加与美国人口中心血管疾病的风险更高有关.
- 这种关联在女性,糖尿病患者,低收入水平或高饮食胆固醇摄入量的人群中可能更为强烈.
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