双pH和Ca2+-响应性PEG-修改支柱[5]arene-based超分子纳米药物输送系统:优秀的货物封装和最小的药物毒性

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Updated: Jul 13, 2026

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
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A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

Published on: December 23, 2016

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Haojie Shao1, Wengui Duan1, Yan Huang2

  • 1Guangxi Colleges and Universities Key Laboratory of Applied Chemistry Technology and Resource Development, School of Chemistry and Chemical Engineering, Guangxi University, 530004, Nanning, China.

Chemistry (Weinheim an der Bergstrasse, Germany)
|June 14, 2024
PubMed
概括

这项研究引入了一种新的pH和Ca2+响应纳米药物输送系统 (NDDS) 用于化疗. 开发的系统增强了抗瘤活性,同时减少了不良影响,显示了改善癌症治疗的巨大潜力.

关键词:
药物控制释放的药物控制释放.主机与客人的互动.经PEG修饰的支柱[5]是arene.在pH和Ca2+-双重响应的条件下.

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