在接受急性A型大动脉解剖手术的患者之间与性别相关的差异
Baku Takahashi1, Keiji Kamohara1, Hiroyuki Morokuma1
1Department of Thoracic and Cardiovascular Surgery, Faculty of Medicine, Saga University, Saga, JPN.
Cureus
|June 14, 2024
概括
在急性A型大动脉解剖 (ATAAD) 患者手术后的早期死亡中,男性性别并不能预测. 然而,年龄,发病和手术程序存在差异,这表明需要基于性别的管理策略来改善结果.
科学领域:
- 心血管外科心血管外科
- 胸部外科手术 胸部外科手术
- 大动脉剖析研究研究
背景情况:
- 急性甲动脉解剖A型 (ATAAD) 是一种危及生命的疾病,需要紧急手术干预.
- 了解ATAAD的性别差异对于优化患者管理和结果至关重要.
研究的目的:
- 为了评估被诊断患有ATAAD的患者的性别特征.
- 为了比较接受ATAAD修复的男性和女性患者之间的手术结果.
主要方法:
- 在2004年至2020年期间接受ATAAD修复的213名患者的回顾性评估.
- 对人口统计数据,临床表现,外科手术,住院死亡率和长期生存率的分析.
- 多变量后勤回归用于确定操作死亡率的预测因素.
主要成果:
- 与男性相比,女性年龄较大,表现出更多的非特异性症状,并且从发病到手术的时间较长.
- 上升性大动脉置换在女性中更为频繁.
- 性别在住院死亡率上没有显著差异;男性性别不是早期死亡的独立预测因素.
- 男性的未经调整的10年生存率明显优于女性.
结论:
- 虽然男性性别不是ATAAD早期死亡率的独立预测因素,但患者特征和手术方法存在显著的基于性别的差异.
- 这些差异凸显了在ATAAD的管理中考虑性别特异因素的重要性.
- 针对性,基于性别的管理策略可能会改善ATAAD患者的长期结果.
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