定制干预措施以控制特有碳烯耐药的Acinetobacter baumannii:一个中断的时间序列分析
Vered Schechner1,2, Adi Cohen1, Yehuda Carmeli1,2
1National Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
耐卡巴胺的Acinetobacter baumannii (CRAB) 感染在14年内显著下降. 根据病房类型量身定制的感染控制策略在减少CRAB发病率和血液感染方面被证明是有效的.
科学领域:
- 传染性疾病 传染性疾病
- 医院流行病学 医院流行病学
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 耐卡巴胺的超原始性菌 (Acinetobacter baumannii,简称CRAB) 构成了医院感染的重大挑战.
- 了解时间趋势和干预效果对于CRAB控制至关重要.
研究的目的:
- 检查CRAB感染的时间趋势,在超大流行性医院环境中.
- 评估不同类型医院病房的各种感染控制策略的有效性.
主要方法:
- 对2006-2019年CRAB临床样本的回顾性分析.
- 间断时间序列分析,以评估干预对医院开始的CRAB感染和血液感染 (BSI) 的影响.
主要成果:
- 在2008年和2010年分别达到峰值的CRAB感染和BSI,到2019年减少了三分之二.
- 具体干预措施,如手部卫生,环境清洁,积极监测,素浴,单室隔离和多式联络方法,显示CRAB发病率显著降低.
- 干预成功因病房类型而异,一些病房显示持续下降.
结论:
- 对CRAB的感染控制干预措施是最有效的,当根据每个病房的具体特征和环境量身定制时.
- 一个病房特定的方法对于成功减少CRAB感染至关重要.
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