相关实验视频

Updated: Jul 29, 2026

Detection of Axonally Localized mRNAs in Brain Sections Using High-Resolution In Situ Hybridization
11:24

Detection of Axonally Localized mRNAs in Brain Sections Using High-Resolution In Situ Hybridization

Published on: June 17, 2015

11.8K

STM-ac4C:一种基于选择性核卷积,时卷积网络和多头自我注意力的人类mRNA中N4-乙基丁 (ac4C) 识别的混合模型

Mengyue Yi1, Fenglin Zhou1, Yu Deng1

  • 1School of Information Engineering, Jingdezhen Ceramic University, Jingdezhen, China.

Frontiers in genetics
|June 14, 2024
PubMed
概括

这项研究介绍了STM-ac4C,这是一种新型的深度学习模型,用于准确预测人类mRNA上的N4-乙半氨酸 (ac4C) 修饰位. 这一进步有助于理解mRNA的修改.

关键词:
这是一种N4-乙基胺.深度学习是一种深度学习.多头自我注意的多头自我注意.选择性的内核卷积.时间卷积网络

更多相关视频

Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA12:35

Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA

Published on: November 14, 2017

9.5K
Antibody-Free Assay for RNA Methyltransferase Activity Analysis08:31

Antibody-Free Assay for RNA Methyltransferase Activity Analysis

Published on: July 9, 2019

7.2K

相关概念视频

Nonsense-mediated mRNA Decay02:27

Nonsense-mediated mRNA Decay

The Upf proteins that carry out nonsense-mediated decay (NMD) are found in all eukaryotic organisms, including humans. Each protein has an individual role, but they need to work in collaboration. Upf1 is an ATP-dependent RNA helicase that unwinds the RNA helix. Because Upf1 can unwind any RNA, Upf2 and Upf3 are required to help Upf1 discriminate between nonsense and normal mRNAs.
Usually, Upf3 binds to an Exon Junction Complex (EJC) at mRNA splice sites. If a ribosome fully translates the mRNA,...
Nucleic Acid Structure01:25

Nucleic Acid Structure

The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA has a double-helix structure. The...