新生儿重症监护室中与药物相关问题的药物干预:发生率,类型和可接受性
Norhan Attia Ahmed1, Ehab Ahmed Fouad2, Osama M El-Asheer3
1Department of Clinical Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Frontiers in pharmacology
|June 14, 2024
概括
与药物相关的问题 (DRP) 在新生儿重症监护室 (NICU) 常见. 临床药剂师在识别和解决这些问题方面发挥着至关重要的作用,改善患者的治疗结果.
科学领域:
- 新生儿重症监护室新生儿重症监护室
- 临床药房 临床药房 临床药房
- 药物安全 药物安全
背景情况:
- 与药物相关的问题 (DRP) 是住院新生儿的一个重大问题,目前对其流行率的研究有限.
- 在多学科团队中集成的临床药剂师对于预防和减轻DRPs在这个脆弱人群中至关重要.
研究的目的:
- 在新生儿重症监护室 (NICU) 中识别和分类DRP.
- 确定导致新生儿DRP的因素.
- 记录药剂师行动的干预,结果,接受率和临床意义.
主要方法:
- 在埃及阿苏特大学儿童大学医院的NICU中进行了一项前性描述性医院研究.
- 数据收集时间为2023年8月至11月.
- 与毒品相关的问题使用欧洲制药护理网络 (PCNE) 分类V9.1.1.进行了分类.
主要成果:
- 在316名新生儿中,283名 (89.6%) 患有1723例DRP (平均每名患者5.5).
- 最常见的DRP类型是治疗有效性 (46.4%) 和治疗安全性 (26.4%),主要是由于剂量选择问题 (61.9%).
- 药剂师的干预导致了92%的DRP解决方案,接受率为98.8%,完全实施率为93%.
结论:
- 与药物相关的问题在NICU环境中非常普遍.
- 临床药剂师在识别和解决DRP方面发挥着重要作用.
- 住院时间和药物的数量等因素与DRP发生有显著的相关性.
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