中国的甲状腺癌趋势及其与G20国家进行的比较分析:2020-2040年的预测
Yi Gong1, Qin Jiang1, Mimi Zhai2,3
1Department of General Surgery, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Journal of global health
|June 14, 2024
概括
甲状腺癌的发病率和死亡率在全球范围内不断上升,特别是在中国. 预测显示持续增加,需要加强预防和国际合作,以打击这种内分泌癌症.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 甲状腺癌占内分泌癌症诊断的很大一部分.
- 这项研究的重点是分析和比较中国和G20国家的甲状腺癌模式.
研究的目的:
- 分析和比较中国和G20国家的甲状腺癌发病率和死亡率趋势.
- 预测未来二十年的甲状腺癌趋势.
主要方法:
- 利用了2019年全球疾病负担 (GBD) 数据进行观察纵向研究.
- 雇员结合点回归和ARIMA模型分析趋势并预测未来的发病率和死亡率.
主要成果:
- 从1990年到2019年,甲状腺癌发病率在中国显著增加 (289.6%),男性的发病率更高.
- 虽然G20国家的增长较小,但年龄标准化死亡率 (ASMR) 较高,70岁以上的人群显著增加.
- 高体重指数 (BMI) 是甲状腺癌死亡的一个不断升级的因素,特别是在中国和沙特阿拉伯.
结论:
- 甲状腺癌的发病率和死亡率在中国和G20国家都在上升.
- 超出过度诊断的因素,包括环境和遗传影响,可能有助于这些趋势.
- 加强预防,控制,治疗战略和国际合作至关重要.
相关概念视频
Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K
Cancer Survival Analysis
342
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
342
Tumor Progression
6.3K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.3K
The Thyroid Gland
3.8K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
3.8K
Tumor Immunotherapy
511
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
511


