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门诊动脉硬指数和发生性心房动之间的关系

Christopher J Boos^1,2, Aung Hein², Tom Wardill²

¹Department of Cardiology, University Hospitals Dorset, Dorset, UK.

Clinical cardiology

|June 14, 2024

概括

门诊动脉硬指数 (AASI) 预测了心房动 (AF) 的风险. 较高的AASI表明AF发育增加,但当考虑年龄时,这种关联会减弱.

科学领域:

心脏病学心脏病学
高血压研究高血压研究
血管健康血管健康

背景情况:

动脉刚性和血压变化是心房动 (AF) 的确立危险因素.
门诊动脉硬度指数 (AASI) 是这些风险因素的经过验证的间接指标.
AASI与AF发病率之间的直接关联以前没有被探索过.

研究的目的:

调查AASI和成年人AF发展之间的关系.
要确定AASI是否是事件AF的独立预测器.

主要方法:

一项观察性队列研究,涉及821名成年人 (18-85岁) 在鼻节律.
参与者接受了24小时的门诊血压监测 (ABPM) 进行高血压评估.
随访时间的中位数为4.0年,记录了AF发作.

主要成果:

在随访期间,9.1%的患者至少发生了一次AF发作.
患有AF的患者的AASI平均值明显高于没有AF的患者 (0.52比0.45,p<.001).
在Kaplan-Meier和Cox回归分析中,较高的基线AASI与AF发展的增加显著相关,但在年龄调整后,这种独立性消失了.

结论:

AASI被认为是成年人AF发育的重要预测因素.
年龄与AASI有很强的相关性,而这个因素混了AF的AASI独立预测值.
可能需要进一步的研究来澄清AASI在AF风险分层中的作用,考虑到年龄的影响.

关键词:

在亚洲,亚洲.循环动脉硬度指数 (AMRI) 是指动脉硬度指数.门诊式的血压管理系统.心房动是心房动的一种.

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