在童年后期内化症状的个体差异:在皮层厚度,遗传和环境差异的变异分解
Anneli D Tandberg1, Andreas Dahl2,3, Linn B Norbom1
1Department of Psychology, PROMENTA Research Center, University of Oslo, Oslo, Norway.
Developmental science
|June 14, 2024
概括
儿童的大脑发育显示皮层厚度与内化症状之间的联系很小. 相反,遗传和家庭环境在儿童后期显著影响这些症状.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 行为遗传学 行为遗传学
背景情况:
- 在童年后期和青春期早期,发育中的大脑表现出显著的变化,包括皮质稀释.
- 在这个发育期内,内化症状往往会增加,但它们与皮质厚度的关系仍然不清楚.
- 之前关于皮层厚度和内化症状的研究已经产生了不一致的结果.
研究的目的:
- 在一大群儿童中,研究脊柱状皮质厚度与内化症状之间的关联.
- 量化皮层厚度差异对内化症状变化的贡献.
- 为了比较皮质厚度与遗传和环境因素对内化症状的影响.
主要方法:
- 利用一种新的统计方法来评估个体在顶点上皮质厚度差异对内化症状的综合影响.
- 从青少年大脑认知发展 (ABCD) 研究中分析了8763名年龄在8.9至11.1岁的儿童的数据.
- 将护理人员报告的内化症状的差异分解为皮质厚度,添加性遗传学,共同的家庭环境和独特的环境因素的贡献.
主要成果:
- 皮层厚度的个体差异解释了内化症状变异的不到0.5%.
- 添加性遗传因素占内化症状变异的6%至48%.
- 共同的家庭环境因素解释了内部化症状的百分比为0%至34%.
结论:
- 皮层厚度与童年后期内化症状的关联很小.
- 添加性遗传学和共同的家庭环境因素在内化症状的发展中发挥着重要作用.
- 未来的研究应该关注遗传和环境影响,而不是仅仅关注皮质形态学,以了解内化症状.
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