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门诊患者在支气管肺功能障碍症中使用吸入性皮质类固醇
Cynara Leon1, Amanda Martin1, Lisa R Young1
1Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Pediatric pulmonology
|June 14, 2024
概括
在患有支气管肺功能失调症 (BPD) 的儿童中,吸入性皮质类固醇 (ICS) 与喘诊断和急诊次数增加有关. 在BPD患者的门诊ICS启动与更急性护理使用和更早的喘诊断有关.
科学领域:
- 儿科肺病学 儿科肺病学
- 新生儿科学 新生儿科学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 吸入性皮质类固醇 (ICS) 通常被处方给患有支气管肺功能障碍 (BPD) 的儿童,用于门诊环境中的呼吸和喘症状.
- 了解ICS使用与BPD患者结果之间的关系对于优化护理至关重要.
研究的目的:
- 调查吸入性皮质类固醇 (ICS) 使用和启动与患者特征和支气管发育不良症 (BPD) 儿童的门诊呼吸结果之间的相关性.
主要方法:
- 从2016年至2021年,对661名被诊断患有BPD的儿童进行了回顾性图表审查,这些儿童在门诊肺部诊所接受治疗.
- 收集的数据包括人口统计,ICS的使用和时间,喘诊断和急性护理的使用.
主要成果:
- 在不同时间点启动ICS:NICU出院 (9.2%),NICU后在第一次诊所访问前 (13.9%) 和第一次诊所访问时 (6.9%).
- 门诊性ICS启动与急诊室访问 (aOR:2.68),住院 (aOR:4.81) 和喘诊断 (aOR:3.58) 的更高几率有关.
- 在门诊环境中处方ICS的儿童在较年轻时被诊断患有喘;与NICU BPD严重性得分没有发现任何关联.
结论:
- 与ICS使用和启动相关的门诊BPD表型存在,独立于NICU的严重程度.
- 患有BPD的儿童的门诊ICS启动与随后的喘诊断和急性护理利用率的增加有关.
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