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Updated: Jun 23, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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数百个LTR12C元素的有效激活揭示了由不同的表观遗传机制决定的cis调节功能

Hitoshi Ohtani1,2, Minmin Liu1, Gangning Liang3

  • 1Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

Nucleic acids research
|June 14, 2024
PubMed
概括

内源逆转录病毒的长终端重复 (LTR) 可以调节基因表达. 利用CRISPR激活,研究人员在控制附近蛋白质编码基因的LTR12C元素中确定了两个表观遗传特征.

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