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Updated: Jun 23, 2025

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
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Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

Published on: December 11, 2009

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新型Gαo突变在GNAO1脑病变中与Ric8蛋白相互作用

Gonzalo P Solis1, Alexey Koval1, Jana Valnohova1

  • 1Translational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

The Journal of clinical investigation
|June 14, 2024
PubMed
概括

GNAO1中的突变通过破坏G蛋白信号传递,导致儿科脑病变. 这项研究揭示了与Ric8蛋白的新型相互作用,提供了疾病严重程度的生物标志物.

关键词:
细胞生物学 细胞生物学它们是G蛋白质.遗传性疾病是一种遗传性疾病.遗传学 是一个遗传学.神经系统疾病 神经系统疾病

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Removal of an Internal Translational Start Site from mRNA While Retaining Expression of the Full-Length Protein05:48

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