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Updated: Jun 23, 2025

In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
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基于模型的生物等价性分析,以评估和预测烯酸配方的相对生物可用性

Alejandra Schiavo1,2, Pietro Fagiolino1, Marta Vázquez1

  • 1Department of Pharmaceutical Sciences, Faculty of Chemistry, Universidad de la República, P.O. Box 1157, 11800, Montevideo, Uruguay.

European journal of drug metabolism and pharmacokinetics
|June 14, 2024
PubMed
概括

基于模型的生物等价性 (MBBE) 为评估药物产品生物可用性提供了比传统分析更优质的替代方案. 这种方法在配方之间进行了更好的区分,并在多剂量场景中预测延长释放药物的良好表现.

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