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Updated: Jun 23, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

508

缓慢的G-四重复变形重组和可访问性变化 诱导人体端粒单链DNA中的变化

Arianna N Lacen1, Andrew Symasek1, Alan Gunter1

  • 1Department of Chemistry, University of Alabama at Birmingham, 901 14th Street South, Birmingham, Alabama 35294, United States.

The journal of physical chemistry. B
|June 14, 2024
PubMed
概括

离子 (K+) 在端粒DNA中稳定G四复合体 (G4s),降低了它们的动态性和对补充链的可访问性. 这种形状变化影响了细胞环境中的端粒突起相互作用.

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