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Updated: Jun 23, 2025

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
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绘制课程:对多发性骨髓瘤进行免疫治疗的测序

Meera Mohan1, Oliver Van Oekelen2, Othman Salim Akhtar1

  • 1Division of Hematology/Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
|June 14, 2024
PubMed
概括

化学抗原受体 (CAR) T细胞和双特异性抗体 (bsAb) 疗法为复发性/耐药性多发性骨髓瘤 (MM) 提供了有效的治疗方法. 这些免疫疗法的最佳选择和排序对于最大限度地提高患者的治疗结果至关重要.

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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