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Updated: Jun 23, 2025

Flow Cytometry-based Assay for the Monitoring of NK Cell Functions
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Published on: October 30, 2016

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具有粘附缺陷和降低细胞毒性功能的NK细胞与多发性髓瘤的不良预后有关

Eve Blanquart1, Rüçhan Ekren1, Bineta Rigaud1

  • 1Cancer Research Center of Toulouse, INSERM, Centre National de la Recherche Scientifique, Université Toulouse III-Paul Sabatier, Toulouse, France.

Blood
|June 14, 2024
PubMed
概括

多发性骨髓瘤 (MM) 患者的自然杀手细胞 (NK) 由于CD16/CD226表达率低,导致细胞毒性功能减弱. 这种NK细胞功能障碍在MM进展过程中积累起来,对存活率产生负面影响,并为新的免疫疗法提供信息.

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