衡量皮肤色调校准的外周血液氧和度的股权驱动传感系统 (OptoBeat):开发,设计和评估研究
Alexander T Adams1,2, Ilan Mandel1, Yixuan Gao1
1Information Science, Cornell Tech, New York, NY, United States.
一个新的超低成本智能手机系统,OptoBeat,准确地测量了不同肤色的外周血液氧和度 (SpO2). 这项技术解决了脉冲氧计校准中的差异,提供可靠的读数到75%的SpO2.
科学领域:
- 生物医学工程 生物医学工程
- 光学传感传感器是什么?
- 医疗器械技术 医疗器械技术
背景情况:
- 商品脉冲氧计对于肤色较深的人来说,校准不够.
- 在基于皮肤色素的外周血液氧和度 (SpO2) 测量中存在显著差异.
- 现有的设备往往无法在人类皮肤色调的全谱范围内提供准确的SpO2读数.
研究的目的:
- 为了测试皮肤色调显著影响脉冲氧计测量的假设.
- 实施一个超低成本的智能手机适配器用于SpO2测量和校准.
- 验证使用皮肤色图像来校准脉冲氧计误差并使用智能手机摄像头测量SpO2.
主要方法:
- 开发了OptoBeat,这是一款基于智能手机的超低成本光学传感系统,使用商品组件和3D打印的剪贴.
- 使用合成皮肤与校准的皮肤色调尺度用于羊血的ex vivo实验.
- 采用定制光学系统,将智能手机屏幕 (闪红色和蓝色) 连接到分析仪和手机的摄像头上.
主要成果:
- 使用RGB值,OptoBeat精确地对皮肤色调进行了分类 (Fitzpatrick类型2,3和5).
- 传统的脉冲氧计显示,皮肤颜色之间有显著的SpO2测量差异 (P<.01).
- 在ex vivo测试中,OptoBeat的SPO2精度在地面真相的1%以内 (R2=0.97),在人体参与者中达到75%和0.5%以内.
结论:
- 皮肤色调显著影响SPO2测量,需要校准.
- 超低成本的OptoBeat系统通过智能手机成像有效校准皮肤色调.
- OptoBeat可靠地测量SPO2,低至75%,减轻偏差并改善可访问性.
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