超声波驱动的气泡与类似软组织边界的相互作用
Victoria Bulycheva1, Michael C Kolios1, Raffi Karshafian1
1Department of Physics, Toronto Metropolitan University, Toronto, Ontario M5B 2K3, Canada; Institute for Biomedical Engineering, Science and Technology (iBEST), A Partnership Between Toronto Metropolitan University and St. Michael's Hospital, 209 Victoria Street, Toronto, Ontario M5B 1T8, Canada; Keenan Research Centre for Biomedical Science, Unity Health Toronto, 209 Victoria Street, Toronto, Ontario M5B 1W8, Canada.
Ultrasonics
|June 14, 2024
概括
气泡大小显著影响了超声波 (US) 暴露期间的动态和软边界相互作用. 较小的气泡表现出较少的运动,而较大的气泡表现出形状的变化和崩的倾向,受频率和边界软度的影响.
科学领域:
- 声学 声学 在声学上.
- 流体动力学 流体动力学
- 生物物理学的生物物理.
背景情况:
- 气泡动力学在各种超声波应用中至关重要.
- 了解气泡墙相互作用是优化超声波治疗的关键.
- 众所周知,泡行为受到外部因素的影响,例如超声波参数和周围介质属性.
研究的目的:
- 在超声波下研究与软边界相互作用的气泡的大小依赖的动态.
- 分析气泡大小,超声波频率和边界特性对气泡行为和边界响应的影响.
- 为优化基于泡和边界特征的超声波条件提供见解.
主要方法:
- 在1kPa软边界附近对三个气泡大小 (1.5μm,15μm,150μm) 的模拟和分析.
- 检查气泡辐射振荡,中心位移和超声频率 (5 kHz - 4 MHz) 的形状变化.
- 对泡振荡的边界偏移和应力反应的评估.
主要成果:
- 较小的气泡表现出较少的惯性运动,并保持球形.
- 较大的气泡显示出显著的形状变化,接近喷气形成,其崩趋势接近它们的自然频率.
- 气泡位移取决于软边界模量,而辐射幅度和速度受到影响很小.
- 较软的边界经历了较少的压力,在特定频率的更大的气泡中观察到共振峰值.
结论:
- 气泡大小和软边界特性极大地影响了超声波诱导的动力学.
- 这些发现为为涉及泡边界相互作用的特定应用量身定制超声波参数提供了指导.
- 优化超声波条件需要考虑泡特性和周围软组织的机械特性.
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