脑瘤患者的状态症管理. 一个队列研究研究
Andria Tziakouri1, Andreas F Hottinger2, Jan Novy1
1Department of Clinical Neurosciences, Neurology service, CHUV and University of Lausanne, Lausanne, Switzerland.
Seizure
|June 14, 2024
概括
在脑瘤患者中,状态 (SE) 发生在五分之一的病例中,并且与其他原因相似地治疗. 结果和治疗响应性在不同的SE病因学上显示了可比的结果.
科学领域:
- 神经学 神经学
- 神经瘤学神经瘤学
- 紧急医疗 紧急医疗
背景情况:
- 状态 (SE) 是一种具有高发病率和死亡率的神经紧急情况.
- 主要脑瘤患者的SE研究不足,缺乏与其他原因相比的详细治疗分析.
研究的目的:
- 确定与瘤相关的SE的频率和治疗模式.
- 为了比较与瘤相关的SE与其他SE病因,关于管理和结果.
主要方法:
- 从2013年1月到2022年12月,对成年SE病例 (不包括后麻醉症) 的回顾性队列研究.
- 对SE管理的分析,耐火性SE率和根据病因分层的临床结果:非新发性,质瘤,脑转移,其他脑瘤.
主要成果:
- 与瘤相关的SE占所有SE发作的1/5 (831名患者中有961次发作).
- 第一线二治疗和第二线抗发作药物 (ASM) 的使用在各组中是相似的.
- 不同的SE病因之间,耐火性SE的发病率和临床结果,包括死亡率是可比的.
结论:
- 与瘤相关的SE是SE的重要原因,并与其他病因相似地进行管理.
- 与瘤相关的SE的治疗响应性和短期临床结果与非新发性SE没有显著差异.
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