帕诺比诺斯塔特和多克索鲁比辛在软组织肉瘤中的协同作用

Yingjun Zhang1, C H Wong2, Connie W C Hui2

  • 1Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China; Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.

概括

这项研究表明,将巴诺比诺斯塔特 (LBH589) 与多克索鲁比结合使用,有效地抑制了小鼠软组织肉瘤 (STS) 瘤的生长,即使用了减少的多克索鲁比剂量. 这种组合针对关键细胞周期基因,为STS提供了有前途的治疗策略.

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