心血管成像结果对药物使用和服药的影响:系统性审查和元分析
Reindolf Anokye1, Jack Dalla Via2, James Dimmock3
1School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia, Australia.
American journal of preventive medicine
|June 14, 2024
概括
心血管成像结果显著增加了像降脂药物这样的药物的开始. 然而,对继续服用药物的影响需要进一步调查.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 药理学 药理学是指药理学的学科.
背景情况:
- 心血管成像提供了关键的健康见解,但其对药物使用的影响尚不清楚.
- 了解成像结果与患者药物坚持之间的联系对于临床决策至关重要.
研究的目的:
- 系统地审查和元分析心血管成像结果对药物使用和药物坚持的影响.
- 量化成像对心血管药物处方模式的下游影响.
主要方法:
- 在主要数据库 (MEDLINE,PsychINFO,EMBASE) 进行系统的文献搜索,直到2024年.
- 从29项研究中提取数据,比较基于动脉状况和成像结果可访问性的结果.
- 聚合几率比率 (ORs) 计算用于评估药物治疗的开始和持续.
主要成果:
- 患有动脉疾病的个体显着更高地开始和继续服用降脂药物 (LLM),抗高血压药物和抗血小板药物.
- 在查后,LLM的使用在患有病动脉的人中增加了2.7倍,在患有正常动脉的人中增加了1.5倍.
- 在成像组与无成像组相比,观察到LLM启动的显著增加,尽管继续率没有显著差异.
结论:
- 心血管成像有效地促使人们开始使用关键药物,特别是LLM,以应对已识别的风险.
- 目前,证据表明,在心血管成像后,改善了药物持续治疗的情况.
- 需要进一步的研究,以充分阐明成像对药物坚持的长期影响.
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