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Updated: Jun 23, 2025

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对WDR5与MBD3C WIN基因复合的结构研究揭示了一个独特的结合模式

Yang Yang1, Li Xu2, Shuting Zhang1

  • 1School of Life Sciences, Anhui University, Hefei, Anhui, China.

The Journal of biological chemistry
|June 14, 2024
PubMed
概括

研究人员使用结构生物学阐明了WDR5-MBD3C相互作用机制. 这揭示了甲基-CpG结合域3异型C (MBD3C) 如何结合WD重复含有蛋白5 (WDR5),帮助向药物设计.

关键词:
在 MBD3C 里面,你会看到 MBD3C.这是WDR5的WDR5.在WIN图案中,使用WIN图案.晶体结构 晶体结构独特的绑定模式 独特的绑定模式

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