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Updated: Jun 23, 2025

ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast
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描述Cwc2,U6 snRNA和Prp8相互作用的特征,这些相互作用在剪接的第一步和第二步之间过渡时被Prp16 ATPase破坏稳定

Jadwiga Meissner1,2, Katarzyna Eysmont1, Katarzyna Matylla-Kulińska

  • 1IMol, Polish Academy of Sciences, 02-247 Warsaw, Poland.

RNA (New York, N.Y.)
|June 14, 2024
PubMed
概括

拼接体在拼接步骤之间重新排列其催化中心. Prp16 ATPase,Cwc2,Prp8和U6 RNA调节了这个过程,揭示了spliceosome催化作用的关键相互作用.

关键词:
Prp16 的使用方法.这就是为什么Prp8是Prp8.在U6 snRNA中.结合体的催化中心.过渡状态的形态变化.

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