相关实验视频

Updated: May 1, 2026

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

基托基水凝:交叉连接策略对质性质的影响

Nelmary Roas-Escalona¹, Frederic Becquart¹, Thierry Delair²

¹Universite Claude Bernard Lyon 1, INSA Lyon, Université Jean Monnet, CNRS UMR 5223, Ingénierie des Matériaux Polymères, F-42023 Saint-Étienne Cédex 2, France.

Carbohydrate polymers

|June 14, 2024

概括

用乙烯点击化学方法比较了基托水凝的两种交叉连接策略. 与聚合物-聚合物方法相比,聚合物-分子方法产生了更快的凝和更强的共价凝.

科学领域:

生物材料科学生物材料科学
聚合物化学聚合物化学
化学工程是化学工程的重要组成部分.

背景情况:

酸盐 (CS) 是一种多功能生物聚合物,具有凝形成的潜力.
共价基凝提供了增强的稳定性和可调节性质.
乙烯的点击化学在温和条件下提供高效和特定的交叉连接.

研究的目的:

研究和比较两种不同的交联策略,以制备基托基共价基凝.
评估功能组扩散 (聚合物结合与自由分子) 对凝动力学和水凝特性的影响.
分析由此产生的水凝网络结构和机械性能.

主要方法:

在水性介质中与乙烯 (CS-ene) 和硫醇 (CS-SH) 组进行基托桑功能化.
两种 thiol-ene 交联策略的比较:聚合物-聚合物 (CS-ene + CS-SH) 和聚合物-分子 (CS-ene + di(乙烯基醇) dithiol).
风湿学测量以评估水凝的凝动力学和机械性能.

主要成果:

聚合物分子策略 (S2) 呈现出更快的凝动力学,这是由于二醇交叉连接剂的流动性更高.
使用聚合物分子策略获得具有较高储存模量的更强的水凝,与功能化程度相关.
聚合物-聚合物策略 (S1) 导致较弱的凝,其特性与初始的聚合物度和纠有关.
这两种策略都产生了具有最小结构缺陷的同质网络.

结论:

交叉连接策略的选择显著影响基托基共价水凝的动力学和特性.
聚合物分子方法在实现快速凝和强大的水凝形成方面优越.
二烯点击化学提供了一种可靠的方法,用于创建定义良好的酸盐凝网络.

关键词:

基托桑是一种酸盐.交叉连接策略交叉连接策略水凝是一种水凝.类风病学类风病学类风病学乙烯 - - 乙烯 - - 乙烯 - - 乙烯

更多相关视频

A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies

A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies

Published on: January 14, 2020

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

相关概念视频

Noncovalent Attractions in Biomolecules

Noncovalent Attractions in Biomolecules

Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...

Polymer Classification: Architecture

Polymer Classification: Architecture

Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...

Bending of Members Made of Several Materials

Bending of Members Made of Several Materials

In analyzing a structural member composed of two different materials with identical cross-sectional areas, it is crucial to understand how their distinct elastic properties affect the member's response under load. The analysis involves assessing stress and strain distributions using the transformed section concept, which accounts for variations in material properties.
Hooke's Law determines stress in each material, stating that stress is proportional to strain but varies due to each material's...

Testing Water Quality

Testing Water Quality

When the quality of water for concrete preparation is uncertain, its impact on the setting time of cement and compressive strength of mortar is assessed by comparison with de-ionized or distilled water benchmarks. American Society for Testing and Materials (ASTM) C1602 requires the setting times to be within 90 minutes of the control, British Standard (BS) 3146:1980 allows a 30-minute variance in the initial setting, while British Standards European Norm (BS EN) 1008 specifies initial setting...

Plasticizers

Plasticizers

Water-reducers, or plasticizers, are chemical admixtures used in concrete to improve strength and workability. These additives reduce the water-cement ratio without compromising workability, lower the cement content while maintaining the same workability, or increase workability to assist concrete placement in inaccessible areas.
Plasticizers function by using surface-active agents to create repulsive electrostatic forces between cement particles. This dispersion enhances the concrete's...

Permeability of Concrete

Permeability of Concrete

Permeability in the context of concrete refers to how easily liquids or gases can pass through the material. This quality is crucial for assessing the water-tightness and durability of concrete structures and their resistance to chemical attacks. Concrete permeability can be determined through comparative laboratory tests. These tests typically involve sealing a concrete specimen from the sides, applying water pressure to the top surface with pressure, and measuring the amount of water passing...