尺寸很重要:丸总体积可以预测坦纳V型静脉患者的精子数量
Alexander H Fang1, Israel Franco2, Joseph M Pizzuti3
1SUNY Downstate Health Sciences University, College of Medicine, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Journal of pediatric urology
|June 14, 2024
概括
青少年男性的静脉瘤可以影响生育能力. 丸总体积 (TTV) 低于29.5cc,显著增加异常精液分析 (SA) 的风险,预测值为96.2%.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 生殖医学 生殖医学
- 青少年健康 青少年健康
背景情况:
- 静脉影响14-29%的青少年男性,关于其对生育能力的影响仍在争论中.
- 在青少年中获得精液分析 (SA) 可能具有挑战性,需要客观地测量生育能力.
- 丸体积差异 (TVD),静脉等级和丸总体积 (TTV) 是潜在的客观标志物.
研究的目的:
- 调查TVD,静脉等级和TTV与精子参数之间的关系,特别是总运动精子数 (TMSC).
- 确定客观的超声波标记物,以预测患有水瘤的青少年男性的异常精液分析.
主要方法:
- 在14年内对486名Tanner V青少年男性进行了回顾性图表审查.
- 纳入标准:可触摸的,未经手术的左侧静脉,至少有一个SA和超声波.
- 统计分析包括多变量后勤回归和接收器操作特征分析.
主要成果:
- 29.5cc的TTV切线被确定为异常TMSC (<900万/射精) 的预测指标,预测值为96.2%,赔率为6.08 (p < 0.001).
- 超过20%的TVD没有达到统计学意义 (odds比=1.66,p=0.50).
结论:
- 低于29.5cc的TTV与异常SA的几率增加六倍有关.
- 超声波测量,特别是TTV,可以帮助风险分层,并为患有静脉的青少年进行手术干预提供咨询.
- 个性化患者管理至关重要,考虑到年龄,TTV和SA结果来指导治疗决策.
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