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Updated: Jun 23, 2025

Measuring RAN Peptide Toxicity in C. elegans
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这三种MutL复合体都需要在人体干细胞模型中进行重复扩张,该模型是CAG重复扩张介导的谷氨胺酶缺乏症

Bruce Hayward1, Daman Kumari1, Saikat Santra2

  • 1Section On Gene Structure and Disease, Laboratory of Cell and Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.

Scientific reports
|June 14, 2024
PubMed
概括

重复扩散疾病 (REDs) 具有共同的机制. DNA修复蛋白质PMS2,MLH3和PMS1对于全球发育迟缓,渐进性无氧和高胺 (GDPAG) 的重复扩张至关重要.

关键词:
总体而言,GDPAG就是一个GDPAG.这就是GLSD GLSD.谷氨酸酶缺乏障碍 谷氨酸酶缺乏疾病微卫星的不稳定性是微观的不匹配的修复 (MMR)重复扩张疾病重复扩张疾病

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