侵入性机械通风参数对COVID-19相关ARDS死亡率的预测值:一个回顾性队列研究
Luis Gutiérrez1, Karina Araya2, Mara Becerra2
1Servicio de Medicina Física y Rehabilitación, Hospital El Carmen de Maipú, Camino A Rinconada 1201, Santiago, Chile. klg.lgutierrez@gmail.com.
在COVID-19后的患者中,管理侵入性机械通风 (IMV) 是至关重要的. 在IMV期间更高的驾驶压力和呼吸率与重症监护室 (ICU) 幸存者的死亡率增加有关.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- COVID-19可能导致急性呼吸困扰综合征 (ARDS),需要在重症监护室 (ICU) 进行侵入性机械通风 (IMV).
- 在COVID-19患者中IMV的临床管理随着经验的发展而发展.
研究的目的:
- 为了评估COVID-19后入住ICU的患者的IMV变量.
- 确定IMV参数与该患者队列中的死亡率之间的关系.
主要方法:
- 一个观察性的,回顾性的研究设计.
- 从101名患者收集的数据,分为存活 (SG) 和不存活 (NSG) 组.
- 提取的临床数据包括病史,动脉气体,IMV持续时间和特定的IMV参数.
主要成果:
- 总体死亡率为32%.
- 没有生存的组 (NSG) 在IMV72小时后显示呼吸速率 (RR),驾驶压力 (DP) 和通风速率 (VR) 显著下降,静态合规性 (Cest) 和PaO2/FiO2比率增加.
- 多发病率,DP和VR独立地与更高的死亡概率有关.
结论:
- 特定的IMV参数,如DP和VR,以及多发病率和男性性别,与COVID-19后患者的死亡风险增加有关.
- 该研究强调了监测和调整IMV设置以改善结果的重要性.
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