患有慢性咳的患者服用含有阿片类药物的处方
Michael Weiner1,2,3, Ziyue Liu2, Jonathan Schelfhout4
1Indiana University Center for Health Services and Outcomes Research, Regenstrief Institute, Inc., 1101 West 10th Street, Indianapolis, IN 46202-4800, USA.
Therapeutic advances in respiratory disease
|June 15, 2024
概括
含有阿片类药物的止咳药被处方给大约20%的慢性咳患者. 在慢性咳患者中,这些药物使用率是慢性咳患者的两倍,特别是那些有医疗补助的患者.
科学领域:
- 肺部病理学 肺部病理学
- 药理学 药理学是指药理学的学科.
- 医疗信息学 医疗信息学
背景情况:
- 慢性咳 (CC) 影响大约10%的成年人群.
- 对阿片类药物用于控制CC的使用仍未得到充分研究.
研究的目的:
- 在被诊断患有慢性咳的患者中调查含有阿片类药物的止咳药 (OCCS) 的处方模式.
- 用电子健康记录数据分析OCCS处方趋势.
主要方法:
- 使用美国中西部的电子健康记录进行了一项回顾性队列研究.
- 慢性咳在56-120天的时间内通过至少三次咳的医疗接触来确定.
- 统计分析包括学生的t测试,皮尔森的千平方和零膨胀的波桑模型.
主要成果:
- 在23210名慢性咳患者中,大约20%接受了OCCS处方.
- 与非慢性队列相比,患有慢性咳的患者被处方OCCS的可能性是慢性咳的两倍.
- 在慢性咳患者中,医疗补助 (38%) 与商业保险 (15%) 的患者中,OCCS的处方更为频繁.
结论:
- 阿片类药物在治疗慢性咳方面发挥着重要作用.
- 需要进一步的研究,以了解阿片类药物的有效性在治疗慢性咳.
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