人参补充剂对脂质特征的影响:GRADE评估的系统审查和随机对照试验的剂量反应元分析
Seyyed Mostafa Arabi1,2, Mostafa Shahraki-Jazinaki3, Maryam Nayyer Abadi1,4
1Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Current pharmaceutical design
|June 15, 2024
概括
帕纳克斯人参补充剂没有显著改变脂质特征,包括甘油三,总胆固醇,HDL-C和LDL-C. 需要进一步的研究来探索人参.
科学领域:
- 心血管健康 心血管健康
- 药理学 药理学是指药理学的学科.
- 营养科学 营养科学
背景情况:
- 心血管疾病 (CVD) 是导致死亡的主要原因,血清脂质起着关键作用.
- 保持最佳的脂质水平对于预防心血管疾病至关重要.
- 人参中的活性化合物金色化物可能会影响脂质代谢.
研究的目的:
- 系统地审查和元分析Panax人参对脂质资料的影响.
- 综合关于人参在治疗失脂症和预防心血管疾病方面的潜力的证据.
主要方法:
- 29个随机对照试验 (RCT) 的系统审查和元分析.
- 对三甘 (TG),总胆固醇 (TC),HDL-C和LDL-C的评估影响.
- 在数据库 (MEDLINE,Scopus,Web of Science) 进行搜索至2024年1月.
主要成果:
- 在补充人参后,没有观察到TG,TC,HDL-C或LDL-C水平的统计学意义上的变化.
- 权重平均差异 (WMD) 和95%信心区间 (CI) 没有显示出显著的影响.
结论:
- 目前的证据表明,人参不会显著影响脂质配置参数.
- 需要进一步的针对特定疾病的精心设计的RCT来澄清人参在脂质管理中的作用.
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