包装年和戒烟之间的关联在血管干预后的结果上
Sherene E Sharath1, Justin Chin-Bong Choi2, Jade Ollison3
1Operative Care Line/Research Service Line VA New York, Harbor Healthcare System, Brooklyn, New York; Department of Surgery, State University of New York Downstate Health Sciences University, Brooklyn, New York.
在高风险的血管手术之前戒烟似乎不会增加术后风险,无论吸烟史. 这一发现表明,戒烟是有益的,无论其持续时间或强度如何.
科学领域:
- 血管外科 血管外科
- 胸部外科手术 胸部外科手术
- 公共卫生 公共卫生
背景情况:
- 吸烟组年史和戒烟时间对高风险患者的术后结果的影响尚不清楚.
- 这项研究调查了吸烟包年和戒烟持续时间如何改变吸烟和术后不良事件之间的关联.
研究的目的:
- 为了确定吸烟组年史和戒烟时间是否影响高风险血管干预后的术后发病率和死亡率.
- 分析吸烟状态,戒烟持续时间,包年史和不良手术结果之间的关系.
主要方法:
- 从2010年至2019年连续接受开放血管手术 (胸腔,大动脉,下) 的患者的回顾性分析.
- 定义的活跃吸烟是手术当天的吸烟;计算的戒烟时间从戒烟日期到手术日期.
- 使用后勤和考克斯回归来评估非活跃吸烟者的戒烟持续时间和包年史之间的关联和相互作用,以30天死亡率和发病率的复合结果.
主要成果:
- 1087名患者接受了1640次高风险血管干预;非活跃吸烟者的中位数包年为40.0,活跃吸烟者的中位数包年为46.0.
- 平均戒烟时间为15.5年.
- 无论是活跃吸烟状态,戒烟持续时间,还是包年史,都没有独立预测30天后术后死亡率或发病率的增加 (相互作用P=0.11).
结论:
- 积极吸烟,戒烟持续时间和包年病史与高风险血管干预后术后发病率或死亡率的增加无关.
- 这些发现突显了戒烟的好处,不管吸烟史的强度或持续时间如何.
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