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在1型糖尿病怀孕期间使用Minimed 780G先进混合闭环系统的真实数据:一中心观测研究
Ana Munda1, Chiara Kovacic2, Drazenka Pongrac Barlovic1
1Clinical Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Slovenia.
Journal of diabetes and its complications
|June 15, 2024
概括
混合闭环系统 (HCLs) 改善了1型糖尿病孕妇的血糖控制. 虽然大多数都达到了目标,但它并没有始终防止怀孕年龄大的婴儿.
科学领域:
- 内分泌学 在内分泌学.
- 生殖医学 生殖医学
- 医疗技术 医疗技术 医学技术
背景情况:
- 患有1型糖尿病的孕妇的血糖控制对孕妇和胎儿的结果至关重要.
- 混合闭环系统 (HCL) 提供先进的自动化胰岛素输送,但它们在怀孕中的有效性需要进一步评估.
研究的目的:
- 评估Medtronic Minimed 780G HCL系统在1型糖尿病妇女怀孕期间控制血糖的有效性.
主要方法:
- 一项回顾性观察性研究分析了21名患有1型糖尿病的孕妇的血糖和周产期结局,使用780G HCL系统.
- 用独立的t测试对三个月的数据进行了比较,并探索了血糖参数和围产期结果之间的关联.
主要成果:
- 在整个怀孕期间,时间范围 (TIR) 逐渐增加,从第一季度的64.0%增加到第三季度的75.7%.
- 平均传感器葡萄糖水平在三个月内下降,表明血糖控制得到改善.
- 尽管实现了TIR目标,但该系统并没有始终防止孕期大婴儿的分娩;发生了一次酸性症事件,没有严重的低血糖症.
结论:
- 在现实环境中,Medtronic Minimed 780G HCL系统在大多数患有1型糖尿病的孕妇中促进了达到推的血糖目标.
- 虽然对血糖管理有效,但对围产期结果的仔细监测仍然至关重要.
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