硫法迪亚降解和抗生素耐药细菌因铁基石墨生物炭和过氧化硫酸盐系统不活化之间的机制差异
Yanbing Ma1, Shengjun Xu2, Yan Huang1
1College of Resources and Environment, Henan Agricultural University, Zhengzhou 450002, China.
Journal of hazardous materials
|June 15, 2024
概括
这项研究表明,KFeB/PS有效地通过不同的机制去除抗生素和ARB. KFeB/PS提供先进的废水净化方法,通过降解硫黄和使抗生素耐药细菌和基因失活.
科学领域:
- 环境化学环境化学
- 水处理技术水处理技术
- 催化剂是一种催化剂.
背景情况:
- 抗生素和抗生素耐药细菌 (ARB) 构成重大环境风险.
- 硫酸盐 (PS) 激活是一种有前途的先进氧化过程,用于污染物降解.
- 基于生物炭的催化剂为环境修复提供可调节的特性.
研究的目的:
- 通过使用K2FeO4激活生物炭 (KFeB) 和用PS.酸取的K2FeO4激活生物炭 (AKFeB) 来研究硫法迪亚 (SDZ) 降解和ARB失活的机制.
- 区分铁站点和石墨结构在污染物清除中的作用.
- 评估对抗生素耐药性基因 (ARG) 和水平基因转移的影响.
主要方法:
- 合成和描述KFeB和AKFeB催化剂.
- 使用KFeB/PS和AKFeB/PS系统进行SDZ降解和ARB失活的批量实验.
- 使用电子转移和自由基路径阐明机制.
- 对ARG去除和结合性转移频率的分析.
- 转录组分析以确定ARG减少的机制.
主要成果:
- 无论是KFeB/PS还是AKFeB/PS系统都类似地降解了SDZ,但只有KFeB/PS显示出显著的ARB失活.
- SDZ降解是通过石墨结构介导的电子转移发生的.
- 由于铁激活的PS产生的自由基导致了ARB无活化,从而有效地去除了ARG.
- KFeB/PS治疗显著降低了ARG的结合转移频率.
- 转录组数据表明膜破坏和ATP合成抑制是减少基因转移的关键因素.
结论:
- KFeB/PS和AKFeB/PS系统表现出不同的污染物降解和细菌失活的机制.
- 由于有效地去除抗生素,ARB和ARG,KFeB/PS系统展示了实际废水净化潜力.
- 这项研究提供了关于在先进的氧化过程中使用碳基催化剂对抗生素和ARB的向控制的见解.
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