一个CuSO4/Bicinchoninic酸/降解糖基稳定和非ROS催化剂系统用于生物分析中的CuAAC反应

Yuchen Wang1, Shi-Chao Lu2, Hui Wen2

  • 1Department of Pharmacology, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xiannongtan Street, Beijing 100050, China.

Bioorganic chemistry
|June 15, 2024
PubMed
概括

这项研究引入了一种新型的催化剂系统,使用降解糖和双酸 (BCA) 进行铜催化酸-酸循环添加 (CuAAC) 反应. 该系统提供了更好的稳定性和更少的活性氧物种,使其非常适合敏感的生物分析.

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