在慢性腰部疼痛中感觉运动整合
Hugo Massé-Alarie1, Muath Shraim2, Paul W Hodges2
1The University of Queensland, NHMRC Centre of Clinical Research Excellence in Spinal Pain, Injury & Health, School of Health & Rehabilitation Sciences, Brisbane, QLD, Australia; Centre Interdisciplinaire de Recherche en Réadaptation et Intégration Sociale (CIRRIS), Université Laval, Québec, Canada.
Neuroscience
|June 15, 2024
概括
慢性腰部疼痛 (CLBP) 改变了感觉运动整合,增加了准脊椎肌肉中的皮质脊髓刺激能力. 这表明改变的 afferent 处理影响了CLBP患者的运动控制.
科学领域:
- 神经科学是一个神经科学.
- 康复科学 康复科学 康复科学
- 生物医学工程 生物医学工程
背景情况:
- 慢性腰部疼痛 (CLBP) 与感觉运动控制受损有关.
- 来自腰椎骨盆区域的 afferent 信号的变化处理可能会影响 CLBP 中的下降运动通路.
研究的目的:
- 为了研究腰椎神经 afferent刺激对对脊柱肌肉的皮质运动控制的影响,在个人与CLBP.
- 为了确定在CLBP中改变的感觉运动整合是否会影响下降的皮质脊髓通道.
主要方法:
- 经磁刺激 (TMS) 用于测量准脊椎肌肉中的运动唤起潜能 (MEP) 幅度.
- 在TMS之前,腰椎神经区域的有害和无害的电磁刺激作为 afferent刺激.
- 计算了MEP/EMG比,以评估皮质脊髓刺激性,控制净运动神经元刺激性.
主要成果:
- 与60毫秒,80毫秒和100毫秒间隔的对照组相比,在CLBP组中,MEP/EMG比率显著更高.
- 单靠对方刺激就导致了在100 ms的CLBP组中更大的EMG振幅降低.
- 这些发现表明,在CLBP中,对准脊椎肌肉的下降皮质脊髓输入有了增强的促进作用.
结论:
- 感觉运动整合在CLBP中发生变化,其特点是皮质脊髓刺激性增加.
- 在CLBP中发生的变异性 afferent处理可能会导致运动控制缺陷.
- 了解这些机制可以为CLBP提供有针对性的干预措施.
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