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Updated: Jun 23, 2025

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog
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Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog

Published on: November 5, 2014

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细胞化酶PADI4和转录抑制剂RING1B在癌细胞中结合

Salome Araujo-Abad1, Bruno Rizzuti2, Lourdes Soto-Conde3

  • 1Cancer Research Group, Faculty of Engineering and Applied Sciences, Universidad de Las Américas, 170124 Quito, Ecuador; IDIBE, Universidad Miguel Hernández, 03202 Elche (Alicante), Spain.

International journal of biological macromolecules
|June 15, 2024
PubMed
概括

研究人员发现,PADI4和RING1B蛋白在癌细胞中相互作用. 这种由GSK484抑制的相互作用表明,潜在的新型癌症疗法可以针对这种蛋白质结合.

关键词:
本质上是无序的蛋白质.异热定位热量计 异热定位热量计分子对接是分子对接.这是NMR的NMR.蛋白质与蛋白质之间的相互作用近距离结合试验测试.

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