长期功能限制和COVID-19后恢复的预测因素:一个多中心前性队列研究
Marla Beauchamp1, Renata Kirkwood1, MyLinh Duong2
1School of Rehabilitation Science, McMaster University, Hamilton, Ont, Canada.
The American journal of medicine
|June 15, 2024
概括
在严重的COVID-19发生一年后,许多患者经历了持久的移动性和认知缺陷. 病前状态和特定的临床因素预测了COVID-19幸存者的长期功能恢复.
科学领域:
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
- 神经学 神经学
- 康复医学 康复医学 康复医学
背景情况:
- 在严重的COVID-19之后,关于长期功能恢复轨迹的数据有限.
- 了解病前状态对于描述COVID-19后的功能结果至关重要.
研究的目的:
- 描述COVID-19住院治疗后1年的功能恢复.
- 在严重的COVID-19患者中确定长期功能和认知恢复的预测因素.
主要方法:
- 在加拿大安大略省住院的254名COVID-19患者的前性队列研究.
- 在急性护理后使用活动测量 (AM-PAC) 移动性和认知度量表.
- 在12个月内评估功能状态,症状,螺旋计,身体表现和心理健康.
主要成果:
- 在12个月后,55.3%的人有运动缺陷,38.8%的人有认知缺陷,与病前水平相比.
- 常见的症状包括疲劳 (44.2%),走路困难 (35.8%) 和呼吸障碍 (33.0%).
- 更好的流动性的预测因素包括更高的先发性流动性,男性性别,更短的住院时间,更少的并发性疾病和更高的FEV1.
结论:
- 严重的COVID-19在感染后一年对功能和认知状态产生了重大和持久的影响.
- 功能性缺陷普遍存在,这凸显了针对性康复策略的需要.
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