良性,非功能性甲状腺结节的射频切除后甲状腺功能的趋势:单一机构审查
Stephanie J Chan1, Madison C Betcher1, Eric J Kuo1
1Division of GI/Endocrine Surgery, Columbia University, New York, NY, USA.
American journal of surgery
|June 15, 2024
概括
对良性甲状腺结节的射频切除 (RFA) 会导致暂时的甲状腺功能低下和甲状腺抗体的增加. 这些变化在治疗后12个月内正常化,随着预期的结节体积减少.
科学领域:
- 内分泌学 在内分泌学.
- 最少侵入性手术的方法
- 甲状腺疾病 甲状腺疾病
背景情况:
- 射频切除 (RFA) 对良性,非功能性甲状腺结节 (NFTNs) 有效.
- RFA对甲状腺功能的影响需要进一步研究.
- 这项研究评估甲状腺激素和抗体水平RFA后NFTNs.
研究的目的:
- 为了评估RFA对甲状腺功能的影响.
- 在RFA后监测甲状腺激素水平 (TSH).
- 在RFA后跟踪甲状腺抗体水平 (Tg和TPO).
主要方法:
- 对185名用RFA治疗良性NFTNs的患者进行了回顾性分析.
- 甲状腺功能测试记录在RFA前和RFA后的3,6和12个月.
- 对结节体积减少和甲状腺激素/抗体趋势的分析.
主要成果:
- RFA导致结节体积显著减少.
- 平均TSH在RFA后3个月短暂增加 (p=0.005).
- 甲状腺抗体水平 (Tg,TPO) 显示过渡性增加,在6个月达到峰值.
结论:
- 良性NFTN的RFA会导致暂时的相对甲状腺功能低下.
- 在RFA后观察到甲状腺抗体的暂时增加.
- 甲状腺功能和抗体水平在RFA后12个月内恢复正常.
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