婴儿牙玩具中化学危险物质的迁移特征和风险评估
Yanan Shao1, Zhijuan Wang1, Haoyang Shi1
1Key Laboratory of Consumer Product Quality Safety Inspection and Risk Assessment for State Market Regulation, Chinese Academy of Inspection and Quarantine, Beijing 100176, China.
Journal of chromatography. A
|June 16, 2024
概括
在婴儿牙具中检测到危险物质,在较小的婴儿中迁移和风险更高. 然而,总体而言,非致癌性风险仍然是可以接受的,这表明婴儿安全使用牙.
科学领域:
- 分析化学 分析化学
- 环境健康 环境健康
- 消费者产品安全 产品安全
背景情况:
- 牙是婴儿必不可少的口腔接触玩具.
- 人们对具中的危险物质和婴儿暴露存在担忧.
- 需要对牙安全进行全面的风险评估.
研究的目的:
- 开发和验证一种检测牙具中危险物质的方法.
- 量化牙具中的残留和迁移的危险物质.
- 评估婴儿暴露于这些物质的非致癌健康风险.
主要方法:
- 气色谱-并联质谱法 (GC-MS/MS) 用于分析.
- 在59个牙样本中检测到20种选的危险物质.
- 使用模拟唾液的迁移研究和通过危险系数 (HQ) 和危险指数 (HI) 的风险评估.
主要成果:
- 在牙样本中检测到15种危险物质,其残留量和检测率各不相同.
- 十二种物质迁移到模拟的唾液中,具有可量化的水平和迁移率.
- 在3-12个月的年龄组,与12-24个月的年龄组相比,观察到更高的HQ和HI值.
结论:
- 开发的GC-MS/MS方法可以有效地检测牙具中的危险物质.
- 婴儿暴露于来自牙具的危险物质存在,但在可接受的非致癌风险水平 (HI < 1) 范围内.
- 风险评估强调,对于较小的婴儿 (3-12个月) 来说,潜在的担忧更大.
相关概念视频
Types of Toxins
1.7K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
1.7K
Socioemotional Development during Infancy
53
Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
Primary Temperament Types
53


