酸盐度和牙后疼痛 - - 揭示最佳平衡:系统性审查和元分析
Niharika Prasad1, Parul Dasson Bajaj2, Ramya Shenoy2
1Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Journal of endodontics
|June 16, 2024
概括
在根管治疗 (RCT) 期间,较低度的甲酸盐 (NaOCl) 显著降低了牙后疼痛 (PEP) 和救援止痛的需要. 这一发现表明,在牙科手术后,患者舒适度可能会有所改善.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 牙科药理学 牙科药理学
背景情况:
- 根管治疗 (RCT) 后的常见问题是后尾牙痛 (PEP) 和止痛药的需求.
- 低酸 (NaOCl) 是RCT中广泛使用的灌剂,使用的度不同.
- Cl度对PEP和止痛药的使用的影响需要进行系统的研究.
研究的目的:
- 系统地审查有关不同酸盐 (NaOCl) 度在根管治疗 (RCT) 期间对后内痛 (PEP) 的影响的文献.
- 评估NaOCl度对经过RCT后的救援止痛需要的影响.
主要方法:
- 在主要数据库 (PubMed,Scopus,Web of Science,Embase) 进行了系统的文献搜索,并注册了PROSPERO.
- 包括随机对照试验,在RCT后的不同间隔评估PEP.
- 进行了元分析,以评估PEP和止痛药摄入量,并使用GRADE评估证据确定性.
主要成果:
- 分析了五项涉及674名患者的随机对照试验.
- 与较高度 (≥5%) 相比,较低的NaOCl度 (≤3%) 与在24小时和48小时内显著降低PEP的可能性有关.
- 接受较低NaOCl度的患者报告PEP中度至重度显著减少,并且需要减少止痛.
结论:
- 低确定性证据表明,较低的NaOCl度可能会在RCT期间降低PEP.
- 中等确定性证据表明,在较低的NaOCl度下,止痛剂需求减少.
- 调查结果表明,由于证据的确定性,谨慎解释.
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