[日本儿童癌症医疗环境的现状和前景]
1Dept. of Pediatrics,Tohoku University Graduate School of Medicine.
Gan to kagaku ryoho. Cancer & chemotherapy
|June 17, 2024
概括
日本建立了专门的儿科癌症中心和有组织的研究小组,将生存率提高到80%以上. 新的疗法和综合性支持正在推进对患有癌症的儿童的护理.
科学领域:
- 在瘤学瘤学.
- 儿科医学 儿科医学
- 癌症研究 癌症研究
背景情况:
- 日本促进癌症控制计划的基本计划优先考虑儿童癌症治疗和支持.
- 卫生,劳工和福利部在2013年指定了15家儿科癌症核心医院和一个中央国家儿童健康和发展中心.
- 由于儿科癌症很罕见,因此需要集中治疗和合作研究,以克服单中心研究的局限性.
研究的目的:
- 总结日本儿童癌症医疗环境的现状和未来前景.
- 突出治疗策略的进步,包括临床研究,分子向疗法和CAR-T疗法.
- 强调儿童癌症患者和幸存者的综合性支持性护理和长期随访的重要性.
主要方法:
- 建立15家儿科癌症核心医院和一个中央国家儿童健康和发展中心.
- 组织日本儿童癌症小组 (JCCG) 和日本儿科白血病/淋巴瘤研究小组 (JPLSG) 开展全国范围的临床研究.
- 对耐火性疾病实施分子向疗法和CAR-T疗法.
主要成果:
- 全国范围内针对儿科固体瘤和血液性恶性瘤进行了30多项临床研究.
- 通过合作研究努力,实现了超过80%的整体生存率.
- 引入先进的疗法,如分子向疗法和CAR-T,以及全面的支持性护理计划.
结论:
- 在建立专门的医疗机构和改善日本儿童癌症治疗结果方面取得了重大进展.
- 需要继续努力,确保及时获得新型治疗剂,并加强全面的支持性护理,以改善生活质量.
- 未来的方向包括优化长期幸存者护理,支持青少年和年轻成人 (AYA) 患者,并推进生育保护选项.
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