在周围动脉疾病患者中使用他类药物
Shweta Agrawal1, Sunil Abhishek Batta2, Deepak Kamath3
1Associate Professor, Department of Cardiology, St. John's Medical College Hospital, Bengaluru, Karnataka, India, Corresponding Author.
患有外周动脉疾病 (PAD) 的患者通常不会接受适当的高强度他类药物治疗,尽管他们患动脉样硬化心血管疾病 (ASCVD) 事件的风险很高. 增加血管床的参与与更高的他类药物强度相关.
科学领域:
- 心血管医学 心血管医学
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 周围动脉疾病 (PAD) 是动脉样硬化心血管疾病 (ASCVD) 事件的重要危险因素.
- 适当的他类药物治疗对于管理PAD患者心血管风险至关重要.
- 指南建议高强度他类药物用于高心血管风险的患者.
研究的目的:
- 评估在被诊断患有PAD的患者中适当使用他类药物治疗.
- 为了评估他类药物使用与PAD患者受影响的血管床数量之间的相关性.
主要方法:
- 追溯横截面研究分析了166名经证实患有PAD的患者的数据.
- 数据包括人口统计,临床因素,实验室结果和治疗方法.
- 逻辑回归确定了对他类药物处方的预测因素;根据ACC/AHA指南定义的高强度他类药物治疗.
主要成果:
- 类药物被处方给了82%的PAD患者,但只有39%的人接受了高强度的类药物.
- 脑血管疾病的存在,口服抗凝剂的使用和双重抗血小板治疗与接受下肢再血管化治疗的几率较低有关.
- 糖尿病是最常见的并发症 (68.86%).
结论:
- 患有PAD的患者在适当的高强度他类药物治疗中治疗不足,尽管他们患心脏不良事件的风险较高.
- 在PAD患者中,多个血管床的参与增加与开始高强度他类药物治疗的可能性更高有关.
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