在被诊断为慢性复发多焦点骨髓炎的患者中,脊椎卷入和脊椎形
Nathan D Rogers1,2, Anastasiya A Trizno1,2, Christopher D Joyce3
1Department of Orthopaedic Surgery, University of Colorado, Boulder.
Journal of pediatric orthopedics
|June 17, 2024
概括
慢性复发性多焦点骨髓炎 (CRMO) 影响28%的患者,近一半的患者经历了脊椎高度的下降. 早期成像和监测对于管理这种炎症性骨疾病和预防永久性脊柱形至关重要.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 骨发育不良症 骨发育不良症
- 炎症性骨疾病 炎症性骨疾病
背景情况:
- 慢性复发性多焦点骨髓炎 (CRMO) 是一种罕见的炎症性骨病.
- 常见的CRMO通常影响长骨,但可以涉及整个骨,包括脊柱.
- 脊柱CRMO可能导致脊椎压缩形,从轻微的结到严重的脊椎平面.
研究的目的:
- 为了确定在大量CRMO患者中脊柱干扰的流行率.
- 评估脊椎CRMO患者脊椎形的频率和严重程度.
- 评估CRMO对脊椎体高度的影响.
主要方法:
- 对2003年至2020年期间诊断的CRMO患者的回顾性审查.
- 使用前性维护的数据库识别脊髓损伤患者.
- 对放射数据的分析,以确定脊椎病变和身高下降的发生率.
主要成果:
- 在170名CRMO患者中,48人 (28.2%) 确诊脊柱干扰.
- 脊椎损伤的患者中有27人 (56.3%) 出现脊椎损伤.
- 这些患者中有23人 (85.2%) 出现了脊椎体高度下降的放射性证据.
结论:
- 大约28%的CRMO患者表现出脊柱干涉.
- 几乎一半的脊柱CRMO患者会出现脊椎体高度的下降.
- 图像 (MRI) 对于检测脊柱CRMO病变至关重要;双酸盐可以防止身高下降的进展.
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