在受控人类感染研究中的美德伦理和未解决的伦理问题
Jeffrey T Poomkudy1, Seema K Shah2,3
1Center for Bioethics and Medical Humanities, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Bioethics
|June 17, 2024
概括
人类受控感染研究 (CHI) 是有争议的. 德行伦理提供了一个框架,以解决CHI的伦理挑战,强调调查员的美德,如诚信和同情心,以确保更安全的研究.
科学领域:
- 生物伦理学生物伦理学
- 医学伦理 医学伦理
- 研究伦理学研究伦理学
背景情况:
- 人类受控感染研究 (CHI) 涉及故意为科学目的感染人类受试者.
- 虽然CHI具有强大的安全记录,但它们在道德上仍然存在争议,特别是在COVID-19大流行期间突出.
- 现有的CHI的伦理分析缺乏通过美德伦理的镜头进行全面的检查.
研究的目的:
- 探索美德伦理在控制人类感染研究中解决未解决的伦理问题的实用性.
- 展示美德理论如何提供一个框架来解决CHI中复杂的道德困境.
- 突出调查员美德在确保CHI期间的道德行为的重要性.
主要方法:
- 哲学分析,将美德伦理应用于CHI中的伦理问题.
- 检查CHI的历史和当代例子.
- 讨论具体的伦理挑战,包括不确定的社会价值,第三方风险和退出限制.
主要成果:
- 某些医疗保健机构提出的伦理问题在当前的文献或法规中缺乏足够的解决方案.
- 这些问题包括不确定的社会价值,对第三方的风险以及撤销权的限制.
- 检查员像谨慎,同情和诚信这样的美德的存在对于在道德上管理这些复杂的CHI至关重要.
结论:
- 德行伦理为解决受控人类感染研究的复杂伦理格局提供了一个有价值的框架.
- 强调调查人员的美德对于解决未解决的伦理问题和确保CHI的负责任行为至关重要.
- 实际意义包括在新的CHI模型中优先考虑经验丰富的调查人员.
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