预防性抗生素在鼻腔莫斯缺陷重建中的使用
Jaclyn Lee1, Elizabeth S Longino1, Nicole G Desisto2
1Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
概括
鼻腔莫斯重建后的预防性抗生素没有减少并发症. 这项研究发现,在接受和不接受抗生素的患者之间,感染或损失率没有差异.
科学领域:
- 皮肤病学 皮肤病学
- 整形外科 整形外科 整形外科
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 鼻子缺陷的莫斯手术需要重建.
- 门诊重建是常见的.
- 预防性抗生素的作用受到争论.
研究的目的:
- 评估预防性抗生素对外科诊断中鼻腔莫斯缺陷的外科重建后的结果和并发症的影响.
主要方法:
- 在一个单一的第三级护理中心进行回顾性队列研究 (2021年7月至2023年6月).
- 包括211名接受鼻腔莫斯重建的成年患者.
- 在接受预防性抗生素和未接受预防性抗生素的患者之间比较结果 (感染,/移植,死亡).
主要成果:
- 55%的患者接受了预防性抗生素.
- 整体并发症率为7.6% (感染3.3%,/移植损失1.4%).
- 在抗生素和非抗生素组之间没有观察到并发症率的显著差异. 化学辐射史和皮肤/复合体移植与并发症有关.
结论:
- 预防性抗生素与在办公室环境下进行鼻腔莫斯重建后的手术后并发症的减少无关.
- 手术部位感染率没有受到预防性抗生素使用的影响.
- 进一步的研究可能会探索特定患者群体中并发症的危险因素.
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